REM sleep disorder following general anesthesia in rats

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• 作者：Katarina Lazic^a ; Jelena Petrovic^a ; Jelena Ciric^a ; Aleksandar Kalauzi^b ; Jasna Saponjic^a ; ^{jasnasap@ibiss.bg.ac.rs} ; ^{jasnasaponjic@yahoo.com}
• 关键词：REM sleep ; Anesthesia ; Sleep disorder ; The pedunculopontine tegmental nucleus ; Rat
• 刊名：Physiology & Behavior
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：168
• 期：Complete
• 页码：41-54
• 全文大小：3107 K
• 卷排序：168

文摘

REM sleep disorder has a significant deleterious impact on postoperative outcome. EEG microstructure during distinct stable anesthetized states is different. Distinct general anesthesia regimens prolonged the post-anesthesia REM sleep in rat. Prolonged REM without atonia was demonstrated only after ketamine/diazepam anesthesia. Pentobarbital anesthesia is beneficial for the post-anesthesia REM sleep in rat.