Structural Insight into Fungal Cell Wall Recognition by a CVNH Protein with a Single LysM Domain
详细信息 查看全文
- 作者：Leonardus M.I. Koharudin1 ; Karl T. Debiec1 ; Angela M. Gronenborn1 ; amg100@pitt.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：LysM domain ; Chitin ; Protein-carbohydrate complex ; NMR ; X-ray crystallography
- 刊名：Structure
- 出版年：2015
- 出版时间：3 November 2015
- 年：2015
- 卷：23
- 期：11
- 页码：2143-2154
- 全文大小：9264 K
文摘
- m" id="list_ulist0010">
- •
A single LysM domain can efficiently interact with chitin constituents
- •
Crystal structures of apo, GlcNAc3-, and GlcNAc4-bound MoCVNH3 were determined
- •
Mannose and GlcNAc oligomers bind to their respective recognition domains selectively
- •
Consensus binding mode between GlcNAc oligomers and a single LysM domain is defined