Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks

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• 作者：Sotirios K. Sotiriou¹ ; Irene Kamileri¹ ; Natalia Lugli¹ ; Konstantinos Evangelou² ; Caterina Da-Ré ; ¹ ; Florian Huber¹ ; Laura Padayachy¹ ; Sebastien Tardy³ ; Noemie L. Nicati¹ ; ³ ; Samia Barriot¹ ; Fena Ochs⁴ ; Claudia Lukas⁴ ; Jiri Lukas⁴ ; Vassilis G. Gorgoulis² ; ⁵ ; ⁶ ; Leonardo Scapozza³ ; Thanos D. Halazonetis¹ ; ⁷ ; ^{thanos.halazonetis@unige.ch}
• 关键词：RAD52 ; DNA replication stress ; break-induced replication ; DNA recombination ; cancer
• 刊名：Molecular Cell
• 出版年：2016
• 出版时间：15 December 2016
• 年：2016
• 卷：64
• 期：6
• 页码：1127-1134
• 全文大小：2097 K
• 卷排序：64

文摘

Mammalian RAD52 is involved in the oncogene-induced DNA replication stress response Mammalian RAD52 functions in the repair of collapsed DNA replication forks Rad52 deficiency prolongs the lifespan of Apcmin/+ mice