Toxicity evaluation of e-juice and its soluble aerosols generated by electronic cigarettes using recombinant bioluminescent bacteria responsive to specific cellular damages

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• 作者：Shiv Bharadwaj^a ; Robert J. Mitchell^b ; Anjum Qureshi^a ; Javed H. Niazi^a ; ^{javed@sabanciuniv.edu}
• 关键词：E-cigarette ; E-juice ; Toxicity ; lux ; Bioluminescence ; Biosensor
• 刊名：Biosensors and Bioelectronics
• 出版年：2017
• 出版时间：15 April 2017
• 年：2017
• 卷：90
• 期：Complete
• 页码：53-60
• 全文大小：1271 K
• 卷排序：90

文摘

Evaluated toxicity of e-liquid and its aerosols generated by e-cigarette using stress-responsive bacteria. Liquid e-juice inhibited growth by repressing genes responsible for cellular stress and repair. Solubilized e-juice aerosols do not inhibit growth but induce cellular stress and repair genes. Direct exposure of e-liquid in high doses could cause total cellular DNA fragmentation.