Cord blood IgG and the risk of severe Plasmodium falciparum malaria in the first year of life

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• 作者：Linda M. Murungi^a ; ^{lmurungi@kemri-wellcome.org} ; Klara Sondé ; n^b ; Dennis Odera^a ; Loureen B. Oduor^a ; Fatuma Guleid^a ; Irene N. Nkumama^a ; Mark Otiende^a ; David T. Kangoye^a ; ^c ; Greg Fegan^a ; Anna Fä ; rnert^b ; ^d ; Kevin Marsh^a ; ^e ; ^f ; Faith H.A. Osier^a
• 关键词：Antibody ; Cord blood ; Severe malaria ; Merozoite
• 刊名：International Journal for Parasitology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：47
• 期：2-3
• 页码：153-162
• 全文大小：538 K
• 卷排序：47

文摘

Severe malaria episodes are rare during the first few months of life. The rate of decay of cord blood IgG is inversely proportional to the starting concentration. Antibody dependent respiratory burst mediated by cord IgG protects from severe malaria during the first 6 months of infancy.