Exploratory urinary metabolomics of type 1 leprosy reactions
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- 作者：Oleg. A. Mayborodaa ; Anouk van Hooijb ; Rico Derksa ; Susan J.F. van den Eedenb ; Karin Dijkmanb ; Saraswoti Khadgec ; Pratibha Thapac ; Chhatra B. Kunwarc ; Deanna A. Haggec ; Annemieke Gelukb ; a.geluk@lumc.nl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Biomarkers ; Diagnostics ; Leprosy ; Metabolomics ; Reactions ; Urine
- 刊名：International Journal of Infectious Diseases
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：45
- 期：Complete
- 页码：46-52
- 全文大小：627 K
文摘
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This is the first study of urinary signatures as biomarkers in human mycobacterial disease.
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A longitudinal analysis of urinary metabolic profiles was performed.
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Urinary metabolic profiles correlated with early signs of leprosy reactions.
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Urine is a promising, non-invasive diagnostic for resource-poor settings.