The Ecology and Evolutionary Dynamics of Meiotic Drive

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• 作者：Anna K. Lindholm¹ ; ^{anna.lindholm@ieu.uzh.ch" class="auth_mail" title="E-mail the corresponding author} ; Kelly A. Dyer² ; René ; e C. Firman³ ; Lila Fishman⁴ ; Wolfgang Forstmeier⁵ ; Luke Holman⁶ ; Hanna Johannesson⁷ ; Ulrich Knief⁵ ; Hanna Kokko¹ ; Amanda M. Larracuente⁸ ; Andri Manser¹ ; Catherine Montchamp-Moreau⁹ ; Varos G. Petrosyan¹⁰ ; Andrew Pomiankowski¹¹ ; Daven C. Presgraves⁸ ; Larisa D. Safronova¹⁰ ; Andreas Sutter¹ ; Robert L. Unckless¹² ; Rudi L. Verspoor¹³ ; Nina Wedell¹⁴ ; Gerald S. Wilkinson¹⁵ ; Tom A.R. Price¹³
• 关键词：extinction ; gametogenesis ; gene drive ; meiosis ; speciation ; transmission distortion
• 刊名：Trends in Ecology & Evolution
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：31
• 期：4
• 页码：315-326
• 全文大小：2537 K

文摘

Meiotic drivers are genetic variants that selfishly manipulate the production of gametes to increase their own rate of transmission, often to the detriment of the rest of the genome and the individual that carries them. This genomic conflict potentially occurs whenever a diploid organism produces a haploid stage, and can have profound evolutionary impacts on gametogenesis, fertility, individual behaviour, mating system, population survival, and reproductive isolation. Multiple research teams are developing artificial drive systems for pest control, utilising the transmission advantage of drive to alter or exterminate target species. Here, we review current knowledge of how natural drive systems function, how drivers spread through natural populations, and the factors that limit their invasion.