Annexin A6 regulates adipocyte lipid storage and adiponectin release

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• 作者：Sabrina Krautbauer^a ; Elisabeth M. Haberl^a ; Kristina Eisinger^a ; Rebekka Pohl^a ; Lisa Rein-Fischboeck^a ; Carles Rentero^b ; Anna Alvarez-Guaita^b ; Carlos Enrich^b ; Thomas Grewal^c ; Christa Buechler^a ; ^{christa.buechler@klinik.uni-regensburg.de} ; Markus Neumeier^a
• 关键词：Intra-abdominal fat ; Obesity ; Lipid droplet ; Lipolysis ; Adipokine
• 刊名：Molecular and Cellular Endocrinology
• 出版年：2017
• 出版时间：5 January 2017
• 年：2017
• 卷：439
• 期：Complete
• 页码：419-430
• 全文大小：2347 K
• 卷排序：439

文摘

Annexin A6 (AnxA6)-depleted adipocytes have increased triglycerides and adiponectin. Serum adiponectin is increased in AnxA6 deficient mice. AnxA6 in 3T3-L1 adipocytes is upregulated by oxidative stress. AnxA6 is induced in white adipose tissues of mice fed a high fat diet.