Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart
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- 作者：Wenjing Xu1 ; Tomasa Barrientos1 ; Lan Mao2 ; Howard A. Rockman2 ; Anthony A. Sauve3 ; Nancy C. Andrews1 ; 4 ; nancy.andrews@duke.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2015
- 出版时间：20 October 2015
- 年：2015
- 卷：13
- 期：3
- 页码：533-545
- 全文大小：3854 K
文摘
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Transferrin receptor 1 mediates iron uptake in the heart
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Cardiac iron deficit leads to metabolic changes and ineffective mitophagy
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Cardiomyocytes require continuous iron availability
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Nicotinamide riboside ameliorates the effects of cardiac iron deficit