Generation of a naïve human single chain variable fragment (scFv) library for the identification of monoclonal scFv against Salmonella Typhi Hemolysin E antigen
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- 作者：Bee Nar Lim ; Chai Fung Chin ; Yee Siew Choong ; Asma Ismail ; Theam Soon Lim ; theamsoon@usm.my" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antibody phage display ; Monoclonal antibodies ; Naï ; ve library ; scFv ; Hemolysin E ; Salmonella enterica serovar Typhi
- 刊名：Toxicon
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：117
- 期：Complete
- 页码：94-101
- 全文大小：823 K
文摘
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A multi ethnic human naïve scFv library was generated.
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A monoclonal scFv antibody against Hemolysin E was identified.
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The monoclonal scFv antibody could be useful for diagnostics and therapeutics.