Anti-Toxoplasma antibodies prevalence and associated risk factors among HIV patients

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• 作者：Dechassa Tegegne¹ ; ^{dachassat@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Mukarim Abdurahaman¹ ; Tadesse Mosissa² ; Moti Yohannes¹
• 关键词：Toxoplasma gondii ; HIV ; LAT ; Seroprevalence
• 刊名：Asian Pacific Journal of Tropical Medicine
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：9
• 期：5
• 页码：460-464
• 全文大小：302 K

文摘

To assess the seroprevalence and associated risk factors of toxoplasmosis among HIV patients in Agaro Town Health Center of Jimma zone.

Methods

Convenient sampling was used to collect blood samples from 135 patients attending anti-retroviral therapy from February to March 2015. Serum samples were tested for anti-Toxoplasma gondii (T. gondii) antibody by using latex agglutination test. Structured questionnaire was used to collect data on socio-demographic and risk factors associated with toxoplasmosis.

Results

Overall seroprevalence of toxoplasmosis was 80.7% (109/135, CI: 74.04–87.36). In multivariate analysis significant association was observed between anti-T. gondii seropositivity and raw meat consumption (OR: 3.514, CI: 1.167–10.581, P = 0.025), knowledge about toxoplasmosis (OR: 5.225, CI: 1.382, P = 0.015) and sex (OR: 4.023, CI: 1.382–19.762, P = 0.015).

Conclusions

Immuno compromised patients showed high rate of seropositivity and thus, it is highly advisable to introduce routine anti-T. gondii antibodies serological screening test prior to ART commencement.