Autoantibodies to neuronal antigens in children with focal epilepsy and no prima facie signs of encephalitis
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- 作者：Peter Borusiaka ; peter.borusiak@helios-kliniken.de" class="auth_mail" title="E-mail the corresponding author ; Ulrich Bettendorfb ; Gert Wiegandc ; Thomas Bastd ; Gerhard Klugere ; f ; Heike Philippig ; Dieter Mü ; nstermannh ; Christian G. Bieni
- 关键词：Pediatrics ; Autoimmune ; GAD65 ; N-methyl-d-aspartate receptor ; VGKC
- 刊名：European Journal of Paediatric Neurology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：20
- 期：4
- 页码：573-579
- 全文大小：271 K
文摘
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5/124 children with focal epilepsy without evidence for encephalitis had autoantibodies.
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We did not find any distinctive features distinguishing antibody positive patients.
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Antibodies in these children are not syndrome specific and probably not pathogenic.
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Antibodies may in some cases be biomarkers for inflammatory processes in a broad sense.