Assessment in vitro of the genotoxicity, antigenotoxicity and antioxidant of Ceratonia siliqua L. extracts in murine leukaemia cells L1210 by comet assay
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- 作者：Aï ; cha Sassia ; b ; Ines Bouhlela ; b ; Nadia Mustaphaa ; b ; Imen Mokdad-Bzeouicha ; b ; Fadwa Chaabanea ; b ; Kamel Ghedirab ; Leila Chekir-Ghediraa ; b ; leila.chekir@laposte.net" class="auth_mail" title="E-mail the corresponding author
- 关键词：Ceratonia siliqua ; Polyphenols ; Comet assay ; Antigenotoxicity ; Cellular antioxidant activity ; Lipid peroxidation
- 刊名：Regulatory Toxicology and Pharmacology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：77
- 期：Complete
- 页码：117-124
- 全文大小：741 K
文摘
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Ceratonia siliqua extracts had cytotoxic effect.
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The two extracts showed no genotoxic effect.
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These extracts showed anti-genotoxic effect to the hydrogen peroxide induced DNA damage.
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Aqueous and TOF extracts had antioxidant activities.