Purification, characterization, synthesis, in vitro ACE inhibition and in vivo antihypertensive activity of bioactive peptides derived from oil palm kernel glutelin-2 hydrolysates
文摘
Four novel ACE inhibition peptides identified in palm kernel glutlein-2 hydrolysate. The peptides showed non-competitive ACE inhibition and relatively good stability. The peptides showed good antihypertensive effect in spontaneous hypertensive rats. The peptides could lower endothelia-1 content without significant cytotoxicity. The peptides could protect vascular endothelial cells from oxidative induced damage.