Cryoablation of Osteoid Osteoma in the Pediatric and Adolescent Population

详细信息    查看全文

• 作者：Morgan J. Whitmore ; MD^a ; C. Matthew Hawkins ; MD^a ; ^b ; ^{Matt.hawkins@emory.edu" class="auth_mail" title="E-mail the corresponding author} ; J. David Prologo ; MD^a ; Kelley W. Marshall ; MD^b ; Jorge A. Fabregas ; MD^d ; Douglas B. Yim ; MD^e ; David Monson ; MD^c ; Shervin V. Oskouei ; MD^c ; Nicholas D. Fletcher ; MD^c ; Roger S. Williams ; DO^a
• 关键词：NSAID ; nonsteroidal antiinflammatory drug ; OO ; osteoid osteoma
• 刊名：Journal of Vascular and Interventional Radiology
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：27
• 期：2
• 页码：232-237
• 全文大小：581 K

文摘

To evaluate the technical feasibility and clinical efficacy of osteoid osteoma (OO) cryoablation in a large, pediatric/adolescent cohort.

Materials and Methods

An electronic medical record and imaging archive review was performed to identify all cryoablations performed for OOs between 2011 and 2015 at a single tertiary care pediatric hospital. The subsequent analysis included 29 patients with suspected OOs treated by cryoablation (age range, 3–18 y; mean age, 11.3 y; 17 boys; 12 girls). Conventional CT guidance was used in 22 procedures; cone-beam CT guidance was used in 7 procedures. Follow-up data were obtained via a standardized telephone questionnaire (23/29 patients; 79.3%) and clinical notes (5/29 patients; 17.2%). One patient was lost to follow-up.

Results

Technical success was achieved in 100% of patients (29/29). Immediate clinical success (cessation of pain and nonsteroidal antiinflammatory drug [NSAID] use within 1 mo after the procedure) was achieved in 27/28 patients (96.4%). Short-term clinical success (cessation of pain and NSAID use for > 3 mo after the procedure) was achieved in 24/25 patients (96%). Long-term clinical success (cessation of pain and NSAID use for > 12 mo after the procedure) was achieved in 19/21 patients (90.5%). Median pain scale score before the procedure was 10 (range, 5–10); median pain scale score after the procedure was 0 (range, 0–8; P < .0001). There were 6 minor complications (21%) and no major complications.

Conclusion

Image-guided cryoablation is a technically feasible, clinically efficacious therapeutic option for children and adolescents with symptomatic OO.