NETosis promotes cancer-associated arterial microthrombosis presenting as ischemic stroke with troponin elevation
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- 作者：Charlotte Thå ; lina ; Melanie Demersb ; c ; Bo Blomgrend ; Siu Ling Wongb ; c ; Magnus von Arbina ; Anders von Heijnee ; Ann Charlotte Laskaa ; Hå ; kan Wallé ; nf ; Denisa D. Wagnerb ; c ; g ; denisa.wagner@childrens.harvard.edu" class="auth_mail" title="E-mail the corresponding author ; Sara Aspbergf
- 关键词：ACS ; acute coronary syndrome ; CHF ; congestive heart failure ; NETs ; neutrophil extracellular traps ; PAD4 ; peptidylarginine deiminase 4 ; H3Cit ; citrullinated histone H3 ; hsTnT ; high sensitivity Troponin T ; G-CSF ; granulocyte colony-stimulating factor ; NIHSS ; National Institute of Health Stroke Scale ; TAT ; thrombin-antithrombin complex ; sP-selectin ; soluble P-selectin ; cfDNA ; cell free DNA ; VTE ; venous thromboembolism ; LMWH ; low-molecular-weight heparin
- 刊名：Thrombosis Research
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：139
- 期：Complete
- 页码：56-64
- 全文大小：1209 K
文摘
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Cancer-associated arterial microthrombosis may be underestimated.
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This hypercoagulable state may be linked to neutrophil extracellular traps.
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Markers of NETs could aid in diagnosing cancer-associated arterial microthrombosis.
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Markers of NETs could aid in diagnosing cancer in arterial microthrombosis.