- 作者：Alberto Ruano-Ravina ; Luciana Prini-Guadalupe ; Juan Miguel Barros-Dios ; Jos¨¦ Abal-Arca ; Virginia Leiro-Fern¨¢ndez ; Ana Isabel Gonz¨¢lez-Silva ; Antonio Golpe-G¨®mez ; Francisco Javier Gonz¨¢lez-Barcala ; Carolina Pena ; Carmen Montero-Mart¨ªnez ; Cristina Mart¨ªnez-Gonz¨¢lez ; Mar¨ªa Jos¨¦ Mejuto-Mart¨ª ; Alej ; ro Veres-Racamonde
- 关键词：Cá ; ncer de pulmó ; n ; Radó ; n residencial ; Españ ; a ; Estudio de casos y controles
- 刊名：Archivos de Bronconeumolog¨ªa
- 出版年：2012
- 出版时间：November, 2012
- 年：2012
- 卷：48
- 期：11
- 页码：405-409
- 全文大小：376 K
Introduction and objective
Residential radon is the second most important risk factor for lung cancer and the first among never-smokers. The objective of this study is to report the concentrations of residential radon in a series of never-smoker cases recruited in a multicenter study of cases and controls in northwestern Spain. In this study, all the hospitals in the Spanish province of Galicia and one from Asturias participated.
Patients and methods
The present article includes a series of cases with residential radon measurements. All the subjects were personally interviewed, 3 ml of blood were taken from each, and they were each given instructions about how to place a residential radon detector in their homes.
Results
Sixty-nine case subjects were recruited, 84 % of whom were women with a mean age of 71, and 81 % of whom had adenocarcinoma. The average concentration of residential radon in the cases was 237 Bq/m3, while the average concentration in the Galician population is 79 Bq/m3. No relationship was observed between the concentration of residential radon and either sex or age at the time of diagnosis of the cases, but there was a tendency towards having a greater concentration in those diagnosed with small-cell and large-cell carcinoma.
Conclusions
The concentrations of residential radon in the cases included are very high at about three times the average concentration of residential radon to which the general population of Galicia is exposed.