First stereoselective pinacol coupling in the [2.2]paracyclophane series

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• 作者：Sergeeva ; Elena V. ; Rozenberg ; Valeria I. ; Antonov ; Dmitrii Yu. ; Vorontsov ; Evgenii V. ; Starikova ; Zoya A. ; et. al.
• 刊名：Tetrahedron: Asymmetry
• 出版年：2002
• 出版时间：June 21, 2002
• 年：2002
• 卷：13
• 期：11
• 页码：1121-1123
• 全文大小：181 K

文摘

The planar chiral N-arylimines of [2.2]paracyclophane undergo stereoselective pinacol coupling under the action of the Zn/Cu couple in the presence of p-TosOH, thus forming N-aryl substituted 1,2-diamines. The stereoselective formation of the asymmetric centers is governed by the planar chiral [2.2]paracyclophanyl moiety.