Weekly paclitaxel therapy for gastric cancer in patients with renal dysfunction: A case report
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- 作者：Kyohei Kanematsu ; Hironori Tsujimoto ; tsujihi@ndmc.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Shinsuke Nomura ; Hiroyuki Horiguchi ; Nozomi Ito ; Kenji Yamazaki ; Shuichi Hiraki ; Suefumi Aosasa ; Junji Yamamoto ; Kazuo Hase
- 关键词：Gastric cancer ; Paclitaxel ; Hemodialysis ; Pharmacokinetics
- 刊名：Annals of Medicine and Surgery
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：11
- 期：Complete
- 页码：26-28
- 全文大小：376 K
文摘
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In Japan, the standard therapy for unresectable advanced gastric cancer is S-1 and cisplatin combination chemotherapy. However, the pharmacodynamics of these agents in patients with renal dysfunction remains unclear.
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We herein present a case of chronic kidney disease (CKD) in which the patient was safely given paclitaxel to treat gastric cancer with peritoneal dissemination.
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Weekly paclitaxel therapy is feasible and effective for patients with advanced gastric cancer and renal impairment.