Potential of atmospheric pressure chemical ionization source in gas chromatography tandem mass spectrometry for the screening of urinary exogenous androgenic anabolic steroids
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- 作者：M. Raroa ; T. Portolé ; sa ; E. Pitarcha ; J.V. Sanchoa ; F. Herná ; ndeza ; L. Garrostasb ; J. Marcosb ; c ; R. Venturab ; c ; J. Segurab ; c ; O.J. Pozob ; opozo@imim.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Anabolic androgenic steroids (AAS) ; Atmospheric pressure chemical ionization (APCI) ; Gas chromatography (GC) ; Tandem mass spectrometry (MS/MS) ; Triple quadrupole (QqQ) ; Doping control analysis
- 刊名：Analytica Chimica Acta
- 出版年：2016
- 出版时间：4 February 2016
- 年：2016
- 卷：906
- 期：Complete
- 页码：128-138
- 全文大小：977 K
文摘
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APCI source has been evaluated for the screening of 16 exogenous AAS in urine.
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Suitable precision was observed for APCI although lower than with EI.
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LODs for APCI were commonly lower.
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GC-APCI-MS/MS method increases the period in which the misuse of 4ClMTD is detected.
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APCI source is an adequate alternative to the traditional EI source in GC–MS.