Small molecule MALDI MS imaging: Current technologies and future challenges
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- 作者：Paul J. Trim ; Marten F. Snel ; marten.snel@sahmri.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：MSI ; Mass Spectrometry Imaging ; IMS ; Ion Mobility Separation ; LDI ; Laser Desorption/Ionization ; MALDI ; Matrix-Assisted Laser Desorption/Ionization ; SIMS ; Secondary Ion Mass Spectrometry ; DESI ; Desorption Electrospray Ionization ; TOF ; Time-Of-Flight ; LAMMA ; Laser Microprobe Mass Analyzer ; Nd ; YAG ; Neodymium-Doped Yttrium Aluminum Garnet ; Q-TOF ; Quadrupole-TOF ; QIT-TOF ; Quadrupole Ion Trap TOF ; FT-ICR ; Fourier Transform Ion Cyclotron Resonance ; APCI ; Atmospheric Pressure Chemical Ionization ; ICP ; I
- 刊名：Methods
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：104
- 期：Complete
- 页码：127-141
- 全文大小：1622 K
文摘
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Imaging of small molecules by MALDI MS is reviewed.
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Instrumentation and experimental design are discussed.
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Current challenges in the field and a future perspective are considered.