The overall incidence densities of venous thromboembolism (VTE) were significantly higher in the aplastic anemia (AA) cohort than in the non-AA cohort (42.3 vs 10.2 per 10 000 person-y). The AA cohort had a 2.56-fold higher risk of VTE than did the non-AA cohort. A substantially high risk of DVT was observed within the first 0.5 years of AA diagnosis.