Potential role of Apoptosis Inducing Factor in evolutionarily significant eukaryote, Dictyostelium discoideum survival

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• 作者：Ashlesha A. Kadam ; Tina Jubin ; Hina A. Mir ; Rasheedunnisa Begum ; ^{rasheedunnisab@yahoo.co.in}
• 关键词：Apoptosis inducing factor ; Reactive oxygen species ; Mitochondrial membrane potential ; Dictyostelium discoideum
• 刊名：Biochimica et Biophysica Acta (BBA) - General Subjects
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：1861
• 期：1
• 页码：2942-2955
• 全文大小：2662 K
• 卷排序：1861

文摘

Our study examines the role of AIF in D. discoideum growth and development. AIF acts as a ROS regulator in D. discoideum cells. Under oxidative stress, AIF down-regulated cells are more prone to cell death.