Cerebrospinal Fluid Flow Studies and Recent Advancements
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- 作者：Erin J. Kelly ; PhD* ; Erin.Kelly@toshiba.com" class="auth_mail" title="E-mail the corresponding author ; Shinya Yamada ; MD ; PhD&dagger ;
- 刊名：Seminars in Ultrasound, CT, and MRI
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：37
- 期：2
- 页码：92-99
- 全文大小：1115 K
文摘
This article provides an overview of magnetic resonance imaging (MRI) techniques used to assess cerebrospinal fluid (CSF) movement in the central nervous system (CNS), including Phase-Contrast (PC), Time-Spatial Labeling Inversion Pulse, and simultaneous multi slice echo planar phase contrast imaging. These techniques have been used to assess CSF movement in the CNS under normal and pathophysiological situations. PC can quantitatively measure stroke volume in selected regions, particularly the aqueduct of Sylvius, as synchronized to the heartbeat. The PC is frequently used to investigate those patients with suspected normal pressure hydrocephalus and a Chiari I malformation. Time-Spatial Labeling Inversion Pulse, with high signal-to-noise ratio, captures motion of CSF anywhere in the CNS over a time period of up to 5 seconds. Variations of PC-MRI improved temporal resolution and included contributions from respiration. With non-invasive imaging such as these, more can be understood about CSF dynamics, especially with respect to the relative effects of cardiac and respiratory changes on CSF movement.