Endosulfan affects uterine development and functional differentiation by disrupting Wnt7a and β-catenin expression in rats
详细信息 查看全文
- 作者：Paola I. Ingaramo1 ; Marí ; a M. Milesi1 ; Marlise Guerrero Schimpf ; Jorge G. Ramos ; Lucí ; a Vigezzi ; Mó ; nica Muñ ; oz-de-Toro ; Enrique H. Luque ; Jorgelina Varayoud ; varayoud@fbcb.unl.edu.ar" class="auth_mail" title="E-mail the corresponding author
- 关键词：Endosulfan ; Uterus ; Implantation ; Wnt7a ; β-catenin
- 刊名：Molecular and Cellular Endocrinology
- 出版年：2016
- 出版时间：15 April 2016
- 年：2016
- 卷：425
- 期：Complete
- 页码：37-47
- 全文大小：5913 K
文摘
- class="listitem" id="list_ulist0010">
- class="label">•
Endosulfan alters uterine Wnt7a/β-catenin expression in prepubertal and adult rats.
- class="label">•
Impaired Wnt signaling is linked to lack of uterine glands during implantation.
- class="label">•
Aberrant Wnt signaling may be involved in endosulfan-induced implantation failures.