MCP-1 levels increased in CSF from sporadic FTD.
In GRN FTD, CSF levels of MCP-1 unchanged.
In GRN FTD, CSF IP-10 levels increased, TNF伪 and IL-15 decreased.
RANTES levels decreased in CSF from patients, with or without GRN mutations.
There is a CSF signature of inflammatory molecules in GRN mutation carriers.