Solid lipid nanoparticles for delivery of Calendula officinalis extract
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- 作者：Lide Aranaa ; Clarisa Saladob ; Sandra Vegac ; Oier Aizpurua-Olaizolad ; Igor de la Aradaa ; Tatiana Suarezc ; Aresatz Usobiagad ; José ; Luis R. Arrondoa ; Alicia Alonsoa ; Fé ; lix M. Goñ ; ia ; Itziar Alkortaa ; itzi.alkorta@ehu.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：SLN ; solid lipid nanoparticles ; PA ; palmitic acid ; SA ; stearic acid ; AA ; arachidic acid ; C ; cholate ; TC ; taurocholate ; TDC ; taurodeoxycholate
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2015
- 出版时间：1 November 2015
- 年：2015
- 卷：135
- 期：Complete
- 页码：18-26
- 全文大小：2435 K
文摘
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Five different SLN formulations have been prepared and characterized.
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An optimal SLN composition has been selected.
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The selected SLN formulation efficiently incorporates Calendula officinalis extract.
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Calendula-loaded SLN are non-toxic and they are rapidly taken up by cells.
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Loading Calendula extracts into SLN improves its re-epithelialization efficiency.