Three new complexes of Cu(II) with 7-azaindole have been synthesized and characterized, a dicopper compound, [Cu(C
7H
5N
2)
2(H
2O)]
2¡¤2CH
3CN,
1, and two heptacopper compounds [Cu
7(C
7H
5N
2)
6(¦Ì
3-OH)
6(¦Ì
2-H
2O)
2(¦Ì
2-CH
3OH)
4](CH
3COO)
2¡¤2C
7H
8¡¤6CH
3OH,
2, and [Cu
7(C
7H
5N
2)
5(CH
3COO)(¦Ì
3-OH)
6(¦Ì
2-H
2O)
4(¦Ì
2-CH
3OH)
2](CH
3COO)
2,
4. The structure of
2 is monoclinic and it crystallizes in the
P21/c space group: a = 13.475(4) ?; b = 12.945(4) ?; c = 23.392(7) ?; ¦Â = 91.232(6)¡ã. It contains a unique Cu
7O
12 core in which a central Cu(II) is situated at an inversion center and is bonded to 6 other Cu(II) ions via bridging oxygen atoms from OH
?, H
2O, and CH
3OH groups. Anionic 7-azaindole ligands bridge between adjacent outer Cu(II) ions and all Cu(II) ions have distorted octahedral coordination geometries. Variable temperature magnetic susceptibility measurements revealed the presence of antiferromagnetic exchange interactions between Cu(II) ions which leads to an S = 5/2 ground state at 1.8 K.
Cytotoxicity and cell proliferation activities of the Cu compounds using human tongue squamous cell carcinoma and normal cells revealed that the compounds stimulated proliferation in both types of cells.