Integrated extraction process to obtain bioactive extracts of Artemisia annua L. leaves using supercritical CO₂, ethanol and water

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• 作者：Hugo A. Martinez-Correa^a ; ^{hamartinezco@unal.edu.co} ; ^{hamartinez@yahoo.com} ; Raphaela G. Bitencourt^b ; Ana Carolina A.V. Kayano^c ; Pedro M. Magalhã ; es^d ; Fabio T.M. Costa^c ; Fernando A. Cabral^b
• 关键词：Artemisia annua L. ; Supercritical extraction ; Artemisinin ; Antimalarial activity ; Phenolic compounds ; Flavonoids
• 刊名：Industrial Crops and Products
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：95
• 期：Complete
• 页码：535-542
• 全文大小：973 K
• 卷排序：95

文摘

Artemisia annua extracts were obtained using supercritical CO2, ethanol and water. Supercritical CO2 on 1st extraction allowed to obtain high artemisinin content. High antimalarial activity was obtained in supercritical and ethanolic extracts. Ethanol and water on 2nd extraction step allowed to obtain phenolic rich extracts.