Multivariate data analysis and metabolic profiling of artemisinin and related compounds in high yielding varieties of Artemisia annua field-grown in Madagascar
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- 作者：John Suberua ; Piotr S. Gromskib ; Alison Nordonb ; Alexei Lapkina ; aal35@cam.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：Artemisia annua ; Multivariate data analysis ; Metabolic profiling
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：5 January 2016
- 年：2016
- 卷：117
- 期：Complete
- 页码：522-531
- 全文大小：1913 K
文摘
A robust method was developed for identification and quantification of dihydroartemisinic acid in crude plant extract.
13 genotypes of A. annua used in various breeding programmes screened for superior metabolic profile.
Multivariate analysis was used to identify biosynthetic associations among 5 artemisinin related compounds.