Increased cerebral blood flow among adolescents with bipolar disorder at rest is reduced following acute aerobic exercise

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• 作者：Bradley J. MacIntosh^a ; ^b ; ^d ; ^{bmac@sri.utoronto.ca} ; Zahra Shirzadi^a ; ^d ; Antonette Scavone^c ; Arron WS Metcalfe^a ; ^c ; Alvi H. Islam^c ; Daphne Korczak^e ; Benjamin I. Goldstein^a ; ^c
• 关键词：Bipolar disorder ; Adolescent ; Acute aerobic exercise ; Cerebral blood flow ; Arterial spin labeling ; Exercise-induced feelings inventory
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：208
• 期：Complete
• 页码：205-213
• 全文大小：782 K
• 卷排序：208

文摘

Measured cerebral blood flow (CBF) at baseline and after recumbent cycling. Baseline frontal CBF was increased in adolescents with bipolar disorder compared to controls. Acute exercise decreased CBF more dramatically in adolescents with bipolar disorder. Exercise-related CBF change was associated with feelings of exhaustion.