Artificial microRNA-derived resistance to Cassava brown streak disease
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- 作者：Henry Wagabaa ; b ; Basavaprabhu L. Patilc ; Settumba Mukasab ; Titus Alicaia ; Claude M. Fauquetd ; Nigel J. Taylore ; ntaylor@danforthcenter.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cassava brown streak disease ; Cassava brown streak virus ; Ugandan cassava brown streak virus ; Artificial microRNAs ; Virus resistance
- 刊名：Journal of Virological Methods
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：231
- 期：Complete
- 页码：38-43
- 全文大小：1340 K
文摘
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amiRNAs were produced for imparting resistance to Cassava brown streak disease.
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transgenic plants were produced expressing amiRNAs against CBSV and UCBSV.
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amiRNAs targeting conserved sequences of P1, NIb and CP genes were efficacious.
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levels of resistance to CBSD correlated with accumulation of detectable miRNA.