An efficient synthetic approach to 10-(1H-1,2,3-triazol-1-yl)pyrimido[1,2-a]indoles was developed.
Only readily available reagents, simple procedures, and short reaction times were used.
Difluoro-benzyne results in the corresponding 2,3-difluoro-pyrimido[1,2-a]indoles.
This procedure will open up new routes for the synthesis of pyrimido[1,2-a]indoles.