Four new phorbol diesters from Croton tiglium and their cytotoxic activities
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- 作者：Xiao-Long Zhanga ; b ; Ashfaq-Ahmad Khanc ; Lun Wanga ; b ; Kai Yud ; Fu Lia ; b ; lifu@cib.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Ming-Kui Wanga ; b ; wangmk@cib.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Croton tiglium ; 4-Deoxy-4β-phorbol diesters ; Cytotoxic activity
- 刊名：Phytochemistry Letters
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：16
- 期：Complete
- 页码：82-86
- 全文大小：444 K
文摘
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Four new 4-deoxy-4β-phorbol diesters were isolated from the seeds of Croton tiglium.
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The structures of the new compounds were elucidated by 1D and 2D-NMR data.
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Compound 4 showed cytotoxic activity against the SNU387 with IC50 value of 0.71 μM.