Gender differences in patients with out of hospital cardiac arrest - A middle eastern perspective

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• 作者：Ashfaq Ahmad A.H. Patel ; Abdulrahman Arabi ; R. Singh ; Jassim Al Suwaidi
• 刊名：Journal of the Saudi Heart Association
• 出版年：2013
• 出版时间：April, 2013
• 年：2013
• 卷：25
• 期：2
• 页码：126
• 全文大小：50 K

文摘

Objectives

To compare the clinical characteristics, treatment and outcome in patients hospitalized following out of Hospital Cardiac Arrest (OHCA) according to gender.

Methods

Retrospective analysis of a registry of patients hospitalized with OHCA over a 20-year period (1991-2010) in Hamad Medical Corporation, Doha, Qatar.

Results

Out of 987 patients admitted with OHCA, 269 patients were female (27.3 % ). Compared to males, females were older (61 + 14 vs 55 + 15 years; p = 0.001), more likely to have diabetes (62.1 % vs 35.5 % ; p = 0.001), hypertension (63.9 % vs 34.7 % ; p = 0.001), chronic renal failure (12.3 % vs 5.6 % ; p = 0.001) and BMI > 30 (41.2 % vs 23.9 % ; p = 0.02) and less likely to be smokers (1.9 % vs 26.6 % ; p = 0.001).

There was a lower incidence of STEMI in the female patients (13.8 % vs 36.1 % ; p =  0.001) with no significant difference in the LV ejection fraction (35 ??#xA0;13 vs 34.5 ??#xA0;13; p = 0.81).

They were less likely to be treated with antithrombotic medications (heparin/LMWH: 27.9 % vs 35.9 % ; p = 0.02; ASA: 47.2 % vs 55.8 % ; p = 0.02; thrombolysis: 4.8 % vs 17.3 % ; p = 0.001), PCI (5.2 % vs 13 % ; p = 0.001) and IABP support (0.7 % vs 4.7 % ; p = 0.003).

In hospital mortality was higher in the female group (65.4 % vs 57.7 % ; p = 0.03).

Conclusion

There are significant differences in clinical characteristics, treatment and outcome in patients admitted with OHCA between male and female patients in our database registry.