Predictors for Recanalization After Intravenous Thrombolysis in Acute Ischemic Stroke

详细信息    查看全文

• 作者：Erik T ; berg Askevold ; Halvor Naess ; Lars Thomassen
• 关键词：Recanalization ; stroke ; thrombolysis ; atrial fibrillation
• 刊名：Journal of Stroke and Cerebrovascular Diseases
• 出版年：2007
• 出版时间：January-February 2007
• 年：2007
• 卷：16
• 期：1
• 页码：21-24
• 全文大小：73 K

文摘

Objective: The purpose of this study was to evaluate clinical aspects of recanalization and to assess variables associated with early recanalization. Methods: In all, 27 consecutive patients treated with intravenous thrombolysis were examined with the National Institutes of Health Stroke Scale (NIHSS) and transcranial Doppler ultrasound at presentation and at 2 and 24 hours after treatment. Results: Recanalization less than 24 hours after treatment was found in 70 % of patients. Patients who recanalized had lower NIHSS score on presentation (P = .01) and significant improvement in NIHSS score at 0 to 2 hours (P = .042) and 0 to 24 hours (P = .002) compared with those who did not recanalize. Atrial fibrillation (P = .04), higher serum glucose values on presentation (P = .05), and more traditional risk factors (P = .05) were associated with no recanalization. Conclusions: Recanalization is associated with clinical improvement. High NIHSS score, atrial fibrillation, high serum glucose, and higher number of risk factors indicate a reduced probability for recanalization.