Immunohistochemical analysis of the gingiva with periodontitis of type I plasminogen deficiency compared to gingiva with gingivitis and periodontitis and healthy gingiva
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- 作者：Idil Kurtulus Waschulewskia ; idilkurtulus@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Aslan Y. Gö ; kbugetb ; Nina M. Christiansenc ; Maike Zieglerc ; Volker Schusterd ; Gerhard Wahla ; Werner Gö ; tze
- 关键词：plg ; plasminogen ; plgdef ; Type I plasminogen deficiency ; PMN ; polymorphonuclear neutrophil ; GCF ; gingival crevicular fluid ; elastase 2 ; neutrophil elastase ; ECM ; extracellular matrix ; MMP-3 ; matrix-metalloproteinase 3 stromelysin 1 ; MMP-7 ; matrix-metalloproteinase 7 ; matrilysin ; PCR ; polymerase chain reaction ; RT ; room temperature ; PAS ; periodic acid-Schiff ; TBS ; tris buffered saline ; BSA ; bovine serum albumin ; TIMPs ; tissue inhibitor of metalloproteinases
- 刊名：Archives of Oral Biology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：72
- 期：Complete
- 页码：75-86
- 全文大小：7712 K
文摘
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Type I plasminogen deficiency is an uncommon chronic inflammation of mucous membranes.
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Fibrin clearance is disturbed in this entity.
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Plasmin(ogen)-independent enzymatic fibrin clearance through elastase, MMP-3, MMP-7 have been shown in this study.
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The exact pathomechanism of this entity needs to be determined.