The role of prostaglandins in the regulation of fish immunity
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- 作者：Victoria Gó ; mez-Abellá ; n ; Marí ; a P. Sepulcre ; mpsepul@um.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：AA ; arachidonic acid ; AGs ; acidophilic granulocytes ; AsLPS ; lipopolysaccharide from Aeromonas salmonicida ; COX ; ciclooxygenase ; CRTH2 ; chemoattractant receptor homologous molecule expressed by T helper 2 cells ; CyPG ; cyclopentenone prostaglandin ; DHA ; docosahexaenoic acid ; dHyKePGD2 ; 13 ; 14-dihydro-15-keto-PGD2 ; diMePGD2 ; 11-deoxy-11-methylene-15-keto PGD2 ; diMePGE2 ; 16 ; 16-dimethyl-PGE2 ; DP1 ; prostaglandin D2 receptor 1 ; EcLPS ; lipopolysaccharide from Escherichia coli ; EIA ; enzyme immunoassay ; EP
- 刊名：Molecular Immunology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：69
- 期：Complete
- 页码：139-145
- 全文大小：633 K
文摘
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Fish leukocytes produce PGs in vitro in response to PAMPs, calcium ionophores and AA or EPA.
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Fish leukocytes produce PGs in vivo upon immunostimulation.
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PGs regulate the main biological activities of fish leukocytes.