Olfactory bulbectomy is a model of major cellular dysfunction in the hippocampus.
Olfactory bulbectomy (OBX) induces behavioral deficits similar to clinical depression.
Imipramine and curcumin reduce hippocampal neuroinflammation in OBX rats.
Citalopram and ZSET1446 improve dentate gyrus neurogenesis in OBX rats.
Nefiracetam, sunifiram and rivastigmine restore LTP in CA1 hippocampus in OBX rats.