Coexistence of Th1/Th2 and Th17/Treg imbalances in patients with post traumatic sepsis
详细信息 查看全文
- 作者：Dublu Lal Guptaa ; dablugupta10@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Sanjeev Bhoib ; sanjeevbhoi@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Teena Mohana ; mohan.teena@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Sagar Galwnkarc ; gcsagar@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; D.N. Raoa ; dnrao311@rediffmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：ISS ; injury severity score ; SOFA ; sequential organ failure assessment assay ; S.I ; Shock Index ; THS ; Trauma hemorrhagic shock ; MOF ; multiple organ failure ; MODS ; multiple organ dysfunction syndrome ; APC ; antigen presenting cells
- 刊名：Cytokine
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：88
- 期：Complete
- 页码：214-221
- 全文大小：1203 K
文摘
- •
The skewing of the ratio of Th17/Treg along with Th2/Th1 may contribute to the pathogenesis of sepsis in THS patients.
- •
T cell anergy, depressed Th1 cytokine production and skewing toward increased Th2 type immune reactivity may be a cause of poor outcome in THS patients.