Peroxisome biogenesis, protein targeting mechanisms and PEX gene functions in plants
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- 作者：Laura L. Crossa ; b ; d ; bsllc@leeds.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Heba Talat Ebeedc ; 1 ; fbsheb@leeds.ac.uk" class="auth_mail" title="E-mail the corresponding author ; hebeed@du.edu.eg" class="auth_mail" title="E-mail the corresponding author ; Alison Bakera ; c ; d ; a.baker@leeds.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：AAA ; ATPases Associated with various cellular Activities ; APEM ; Aberrant PEroxisome Morphology ; EosFP ; Eos Fluorescent protein ; ERAD ; ER Associated Decay ; GET ; Guided Entry of TA proteins ; pER ; peroxisomal ER subdomain ; PEX ; abbreviation for Peroxin ; a protein involved in peroxisome formation ; PMP ; peroxisome membrane protein ; PTS1 ; Peroxisomal targeting signal 1 ; PTS2 ; Peroxisomal targeting signal 2 ; RADAR ; Receptor Accumulation and Degradation in the Absence of Recycling ; RING ; protein domain
- 刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：1863
- 期：5
- 页码：850-862
- 全文大小：1126 K
文摘
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Peroxisomes use 2 types of targeting signal for matrix protein import.
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The receptors bind at the peroxisome membrane, deliver their cargo and are recycled.
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The import machinery is comprised mainly of peroxisomal membrane proteins (PMPs).
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PMPs can insert post translationally but some may traffic to peroxisomes via the ER.
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Proteins involved in peroxisome biogenesis are conserved across plant species.