Chondrogenic differentiation of ATDC5-cells under the influence of Mg and Mg alloy degradation

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• 作者：Adela H. Martinez Sanchez^a ; ^{adela.martinez@hzg.de} ; Frank Feyerabend^a ; Daniel Laipple^a ; Regine Willumeit-Rö ; mer^a ; Annelie Weinberg^b ; Bé ; rengè ; re J.C. Luthringer^a
• 关键词：Cell differentiation ; Chondrogenesis ; Biodegradable materials ; Magnesium alloys
• 刊名：Materials Science and Engineering: C
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：72
• 期：Complete
• 页码：378-388
• 全文大小：2297 K
• 卷排序：72

文摘

Degradation of PMg, and Mg-2Ag do not influence ATDC5 cells growth and chondrogenic redifferentiation. Mg-10Gd enhances fast chondrogenic redifferentiation and expression of hyperthrophic markers on ATDC5 cells. Further evaluation of the effects of PMg, Mg-10Gd and Mg-2Ag in vivo are necessary to confirm its potential for application in growing bones.