Quality of life following completion of treatment for adult acute lymphoblastic leukemia with a pediatric-based protocol

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• 作者：Elena Liew ; Santhosh Thyagu ; Eshetu G. Atenafu ; Shabbir M.H. Alibhai ; Joseph M. Br ; wein
• 关键词：Acute lymphoblastic leukemia ; Leukemia ; Quality of life ; Chemotherapy
• 刊名：Leukemia Research
• 出版年：December, 2013
• 年：2013
• 卷：37
• 期：12
• 页码：1632-1635
• 全文大小：590 K

文摘

Using multiple validated self-report instruments, we evaluated the health-related quality of life (HRQoL) of 29 adult ALL patients a median of 28 months after completing a pediatric-based treatment regimen. Global health was similar to normative data, but leukemia survivors had lower cognitive and social function, and reported more financial difficulty. Fatigue and pain affected 83% and 53% of patients, respectively, and both showed significant inverse correlation with overall health and all functional scales. Vincristine-related peripheral neuropathy was reported by 43%. Although therapy-related symptoms were persistent, long-term ALL survivors have a global HRQoL similar to the general population.