Limited artemisinin resistance-associated polymorphisms in Plasmodium falciparum K13-propeller and PfATPase6 gene isolated from Bioko Island, Equatorial Guinea
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- 作者：Jian Lia ; Jiangtao Chenb ; c ; Dongde Xiec ; Urbano Monsuy Eyid ; Rocio Apicante Matesad ; Maximo Miko Ondo Obonod ; Carlos Sala Ehapod ; Liye Yange ; Huitian Yange ; Min Line ; f ; Konfutea@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Plasmodium falciparum ; Polymorphism ; Artemisinin resistance ; K13-propeller
- 刊名：International Journal for Parasitology: Drugs and Drug Resistance
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：6
- 期：1
- 页码：54-59
- 全文大小：498 K
文摘
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The PfATPase6 mutations were found at positions N569K (7.91%), A630S (1.44%) and I723V (0.72%).
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Only one non-synonymous K13-propeller mutation A578S (2.04%) was observed.
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Limited SNPs of PfATPase6 and K13-propeller indicated no widespread ART on Bioko Island, EG.