An approach to expand description of the pump and co-transporter steady-state current

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• 作者：A.G. Dimitrov ^{agd@biomed.bas.bg}
• 关键词：Transporter ; Na-K-ATPase ; Model ; Affinity ; Ion concentration
• 刊名：Journal of Theoretical Biology
• 出版年：2017
• 出版时间：7 January 2017
• 年：2017
• 卷：412
• 期：Complete
• 页码：94-99
• 全文大小：282 K
• 卷排序：412

文摘

General form of the steady state current valid for arbitrary transporter is proposed. Expression for transporter current valid under very general assumptions is obtained. Link between biophysically based and empirical models of pump is demonstrated. A framework for expanding complexity of empirical models is proposed.