FXYD1 negatively regulates Na+/K+-ATPase activity in lung alveolar epithelial cells
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- 作者：Łukasz A. Wujaka ; b ; c ; Anna Blumea ; Emel Baloğlud ; e ; Małgorzata Wygreckaa ; c ; Jegor Wygowskib ; Susanne Herolda ; Konstantin Mayera ; Istvá ; n Vadá ; sza ; Petra Besuchf ; Heimo Mairbä ; urlc ; Werner Seegera ; b ; Rory E. Mortya ; b ; rory.morty@mpi-bn.mpg.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：ARDS ; TGF-β ; Na+/K+-ATPase ; FXYD ; Ion transport ; Edema
- 刊名：Respiratory Physiology & Neurobiology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：220
- 期：Complete
- 页码：54-61
- 全文大小：1044 K
文摘
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FXYD1, FXYD3 and FXYD5 expression is upregulated in ARDS lungs.
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TGF-β regulates FXYD1 and FXYD3 expression.
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hCMV and mCMV promoters optimally drive gene expression in H441 cells.
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FXYD1 inhibits Na/K-ATPase activity in H441 cells.