Structural basis of the substrate recognition of hydrazidase isolated from Microbacterium sp. strain HM58-2, which catalyzes acylhydrazide compounds as its sole carbon source
刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:22 January 2017
年:2017
卷:482
期:4
页码:1007-1012
全文大小:1562 K
卷排序:482
文摘
The crystal structure of hydrazidase complexed with a substrate is determined. A catalytic triad of Ser-cisSer-Lys in hydrazidase is revealed. His336 in a non-conserved region is a determinant for substrate specificity.