Microbiome and metabolic disorders related to obesity: Which lessons to learn from experimental models?

详细信息    查看全文

• 作者：Audrey M. Neyrinck^a ; Valentina L. Sch&uuml ; ppel^b ; Trevor Lockett^c ; Dirk Haller^b ; Nathalie M. Delzenne^a ; ^{nathalie.delzenne@uclouvain.be}
• 关键词：Microbiota ; Inflammation ; Gut hormones ; High fat diet ; Obesity ; Prebiotic
• 刊名：Trends in Food Science & Technology
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：57
• 期：part_PB
• 页码：256-264
• 全文大小：357 K
• 卷排序：57

文摘

Alterations of the gut microbiota have been related to obesity and metabolic diseases. Microbiota may influence obesity and related diseases by acting on key gut functions. Use of mouse models is crucial to relate gut microbiota and metabolic diseases. Efforts are needed to standardize mouse models of diet-induced obesity with dysbiosis.