Plasma phthalate and bisphenol a levels and oxidant-antioxidant status in autistic children
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- 作者：Meda Kondolota ; medakondolot@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Elif N. Ozmertb ; Ali Ascıc ; Pınar Erkekogluc ; Didem B. Oztopd ; Hakan Gumuse ; Belma Kocer-Gumuselc ; belmagumusel@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Kadriye Yurdakokb
- 关键词：ASDs ; autism spectrum disorders ; BPA ; bisphenol A ; CAT ; catalase ; CV ; coefficient of variation ; DEHP ; di-2-ethylhexyl-phthalate ; DSM-V ; diagnostic and statistical manual of mental disorders-V ; EDCs ; endocrine disrupting chemicals ; GPx1 ; glutathione peroxidase ; GR ; glutathione reductase ; GSH ; glutathione ; GSSG ; oxidized glutathione ; HPLC ; high performance liquid chromatography ; H2O2 ; hydrogen peroxide ; LOD ; limit of detection ; LOQ ; limit of quantification ; LP ; lipid peroxidation ; MDA ; malondialde
- 刊名：Environmental Toxicology and Pharmacology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：43
- 期：Complete
- 页码：149-158
- 全文大小：666 K
文摘
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Plasma phthalate and bisphenol A (BPA) levels were determined in autistic children.
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Oxidant/antioxidant status was also evaluated.
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Plasma BPA levels of children with PDD-NOS were significantly higher than control.
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BPA exposure might be associated with PDD-NOS and oxidative stress.
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Intracellular oxidant/antioxidant imbalance might facilitate its neurotoxicity.