Comprehensive assessment of myositis-specific autoantibodies in polymyositis/dermatomyositis-associated interstitial lung disease

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• 作者：Hironao Hozumi^a ; ^{jubilooreoresagi@ybb.ne.jp} ; ^{hozumi@hama-med.ac.jp} ; Tomoyuki Fujisawa^a ; Ran Nakashima^b ; Takeshi Johkoh^c ; Hiromitsu Sumikawa^d ; Akihiro Murakami^e ; Noriyuki Enomoto^a ; Naoki Inui^f ; Yutaro Nakamura^a ; Yuji Hosono^b ; Yoshitaka Imura^b ; Tsuneyo Mimori^b ; Takafumi Suda^a
• 关键词：Polymyositis ; Dermatomyositis ; Myositis-specific autoantibody ; Interstitial pneumonia ; ARS ; MDA5
• 刊名：Respiratory Medicine
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：121
• 期：Complete
• 页码：91-99
• 全文大小：790 K
• 卷排序：121

文摘

Serum MSAs were comprehensively measured using IP assay in PM/DM-ILD patients. Anti-ARS and anti-MDA5 antibodies were the two major MSAs in PM/DM-ILD. Clinical and radiographical features were different among the MSA subgroups. Assessment of MSAs may be useful for predicting the clinical course and prognosis.